Research Studies



Our purpose is to provide summaries and analyses of studies related to PCOS.


Each entry will cover a single research study. Below, you’ll find a list of research studies with:

  • The title of the paper and the journal (and year) in which it was published.
  • A short description of the purpose of the paper.
  • A simple A to F grade.


Each title in the list links to a separate study page. Each study page provides:

  • A list of the strengths and weaknesses of the paper.
  • A summary and analysis of the paper, with key quotations.
  • Links to abstracts or full-text sources, if available.

It is not our intention to only provide simple summaries of the research. As part of our commitment to grow awareness and understanding of PCOS, we will analyze and critique each paper. Not all science is good science. We want to help you separate the good from the not-so-good; the meaningful from the useless.


Since this is not an exhaustive list of all the research on PCOS, we encourage you to look beyond this site for more resources. The first entry below is a guide to help you get started in discovering and analyzing research.



A Guide to Researching PCOS: Techniques for Finding and Evaluating Research

Our chief science officer gives some tips on how to find and evaluate meaningful PCOS information.

Ovulatory And Metabolic Effects Of D-Chiro-Inositol In The Polycystic Ovary Syndrome

New England Journal of Medicine, 1999

The first human clinical trial of D-chiro-inositol.

Grade: A+



Effects Of D-Chiro-Inositol In Lean Women With The Polycystic Ovary Syndrome

Endocrine Practice, 2002

A clinical trial testing the effects of DCI in lean PCOS women.

Grade: A-

Myo-inositol rather than D-chiro-inositol is able to improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial

European Review for Medical and Pharmacological Sciences, 2011

A clinical trial purporting to measure the difference in effects on oocyte quality between myo and DCI .

Grade: F

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