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Is it Safe to Take Metformin and Chiral Balance D-chiro-inositol?
Metformin (brand names: glucophage, glumetza, fortamet, riomet etc.) is a front-line drug in addressing the insulin resistance commonly associated with PCOS. This drug inhibits gluconeogenesis and may strengthen the interaction between insulin and its receptors, thereby enhancing the insulin response. For some people, it effectively normalizes insulin sensitivity and can promote ovulation. Metformin has numerous side-effects.

D-chiro-inositol (DCI) addresses insulin resistance in a slightly different way, by ensuring the body has sufficient DCI to respond to to insulin normally, as there is some evidence that women with PCOS are deficient in DCI. Not surprisingly, DCI has no side-effects.

DCI addresses the putative cause of insulin resistance whereas Metformin addresses the symptoms. Consequently, no interaction between the DCI and Metformin is expected and they could concievably exhibit synergy. Indeed many people take both Metformin and DCI with no adverse reactions, although DCI may obviate Metformin entirely.
 
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 Article # 16
 Posted on 25-6-2009
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