Prescription drugs and their relationships with Chiral Balance D-chiro-inositol.
Can I take an oral contraceptive and DCI?
Yes, oral contraceptive pills do not interfere with the function of Chiral Balance DCI or vice versa. However, taking birth control can mask many of the symptoms of PCOS, making it difficult to evaluate whether Chiral Balance DCI is having the desired effects. Always consult your physician before discontinuing a birth control regimen.
Is it safe to take Spironolactone and DCI?
Spironolactone (brand names: Aldactone and Spiractin) is an aldosterone antagonist and moderates responsiveness to androgens as well. The medication is often prescribed to manage some of the symptoms of PCOS related to hyperandrogenism, such as hirsutism, androgenic alopecia and acne. Spironolactone is an anti-diuretic. The medication’s anti-androgenic effects are secondary and result from competitively binding to androgen receptors, thereby preventing testosterone and dihydrotestosterone from acting. The drug has side effects.
Chiral Balance D-chiro-inositol (DCI) addresses hyperandrogenism in a different way. The insulin resistance commonly associated with PCOS is the cause of hyperandrogenism, and Chiral Balance DCI address this resistance at its root. By restoring insulin sensitivity, androgen levels may lower to within a normal range and symptoms diminish.
Spironolactone addresses the symptoms of elevated testosterone and Chiral Balance DCI addresses the cause of elevated testosterone. Their very distinct mechanisms suggest little likelihood for interaction. However, we cannot recommend taking them together, as it is possible that each may work well, reducing testosterone levels too much.
Is it safe to Take Metformin and DCI?
Metformin (brand names: Glucophage, Glumetza, Fortamet and Riomet) addresses the insulin resistance commonly associated with PCOS. This drug inhibits gluconeogenesis and may strengthen the interaction between insulin and its receptors, thereby enhancing the insulin response. For some people, Metformin effectively normalizes insulin sensitivity and can promote ovulation. Metformin has side effects.
Chiral Balance D-chiro-inositol (DCI) addresses insulin resistance in a different way. There is evidence that women with PCOS are deficient in DCI. Taking Chiral Balance DCI supplement ensures your the body has sufficient DCI to respond to to insulin normally. Chiral Balance DCI showed no side effects in clinical trials.
Chiral Balance DCI addresses the suggested cause of insulin resistance, whereas, Metformin addresses the symptoms. Consequently, no interaction between Chiral Balance DCI and Metformin has been reported.
Is it safe to Take TZD drugs and DCI?
Thiazolidinediones such as Actos and Avandia are prescribed to address the insulin resistance commonly associated with PCOS. Called TZD drugs or Glitazones, these drugs are often tried after Metformin. Avandia and Metformin are sometimes prescribed simultaneously as the combination drug Avandamet. The drugs bind to PPARs a modulating transcription of insulin-sensitive genes related to metabolism. In a sense, these drugs circumvent the steps of insulin signal transduction that are dysfunctional in insulin resistance. TZD drugs have side effects.
Chiral Balance D-chiro-inositol (DCI) addresses insulin resistance in a different way. There is evidence that women with PCOS are deficient in DCI. Chiral Balance DCI supplement ensures the body has sufficient DCI to respond to insulin normally.
Chiral Balance DCI addresses the suggested cause of insulin resistance whereas TZD drugs address the symptoms. Chiral Balance DCI showed no side effects in clinical trials.
Can you take Clomid/Clomiphene Citrate while on DCI?
The drug clomiphene citrate (brand names: Clomid, Clomifert, Serophene, Milophene) is used to induce ovulation and is a common drug used in treating infertility due to anovulation. D-chiro-inositol (DCI) can be taken safely in conjunction with clomiphene. The insulin sensitizer N-acetyl-cysteine (NAC for short) has been found in one clinical trial to improve the effectiveness of clomiphene. DCI, like NAC, is also an insulin sensitizer and consequently may also improve results for a course of clomiphene. In summary, DCI can be taken safely in conjunction with clomiphene, and it may even be beneficial.